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Mol Ther 2019;27:174957

Advances in brain-targeted delivery strategies and natural product-mediated enhancement of bloodbrain barrier permeability

For context, the underlying lyophilized peptide can remain stable for one to two years or longer when stored correctly before reconstitution, making the post-reconstitution window the most critical and time-limited phase of the entire storage cycle

Phase I: Transformation In the first phase, the liver uses enzymes to begin breaking down fat-soluble toxins into intermediate forms